2024
78. Hu H.*, Kurasawa Y.*, Zhou Q., and Li Z. (2024) A kinesin-13 family kinesin in Trypanosoma brucei regulates cytokinesis and cytoskeleton
morphogenesis by promoting microtubule bundling. PLoS Pathogens, 20: e1012000 (*: co-first authors)
2023
77. Souza Onofre T.*, Pham K.T.M.*, Zhou Q., and Li Z. (2023) The microtubule quartet protein SNAP1 in Trypanosoma brucei facilitates
flagellum and cell division plane positioning by promoting basal body segregation. Journal of Biological Chemistry, 299: 105340
(*: co-first authors)
76. Lee K.J., Zhou Q., and Li Z. (2023) CRK2 controls cytoskeleton morphogenesis in Trypanosoma brucei by phosphorylating β-tubulin to
regulate microtubule dynamics. PLoS Pathogens, 19: e1011270
2022
75. Kurasawa Y.*, Lee K.J.*, Hu H., Pham K.T.M., and Li Z. (2022) Polo-like kinase and Aurora B kinase phosphorylate and cooperate
with the CIF1-CIF2 complex to promote cytokinesis initiation in Trypanosoma brucei. Open Biology, 12: 220197 (*: co-first authors)
74. Pham K.T.M., Zhou Q., Lee K.J., and Li Z. (2022) A Spef1-interacting microtubule quartet protein in Trypanosoma brucei promotes
flagellar inheritance by regulating basal body segregation. Journal of Biological Chemistry, 298: 102125
73. Zhou Q.*, Hu H.*, and Li Z. (2022) KLIF-associated cytoskeletal proteins in Trypanosoma brucei regulate cytokinesis by promoting
cleavage furrow positioning and ingression. Journal of Biological Chemistry, 298: 101943 (*: co-first authors)
72. Kurasawa Y., Lee, K.J., and Li Z. (2022) Structural domains of CIF3 required for interaction with cytokinesis regulatory proteins and
for cytokinesis initiation in Trypanosoma brucei. mSphere, 7: 00047-22
rapid passage in mice. Frontiers in Microbiology, 12: 806626
2021
70. Merrick C.J., Absalon S., Brochet M. Li Z., and Suvorova E.S. (2021) Celebrating microbial diversity: the many cell cycles of the eukaryotic
microbes. Frontiers in Cellular and Infection Microbiology, 11: 738994
69. Lee K.J., and Li Z. (2021) The CRK2-CYC13 complex functions as an S-phase cyclin-dependent kinase to promote DNA replication in
Trypanosoma brucei. BMC Biology, 19: 29
68. An T., Hu H., and Li Z. (2021) The kinetoplastid-specific phosphatase KPP1 attenuates PLK activity to facilitate flagellum inheritance
in Trypanosoma brucei. Science Signaling, 14: eabc6435
2020
67. Kurasawa Y., An T., and Li Z. (2020) Polo-like kinase in trypanosomes: an odd member out of the Polo family. Open Biology,
10: 200189
66. Pham K.T.M., Hu H., and Li Z. (2020) Maintenance of hook complex integrity and centrin arm assembly facilitates flagellum
inheritance in Trypanosoma brucei. Journal of Biological Chemistry, 295: 12962-12974
65. An T.*, Zhou Q.*, Hu H., Cormaty H., and Li Z. (2020) FAZ27 cooperates with FLAM3 and ClpGM6 to maintain cell morphology in
Trypanosoma brucei. Journal of Cell Science, 133: jcs245258 (* co-first authors)
64. Pham K.T.M. and Li Z. (2020) Regulated protein stabilization underpins the functional interplay among basal body components in
Trypanosoma brucei. Journal of Biological Chemistry, 295: 729-742
2019
63. Zhang X., Hu H., Lun Z.-R., and Li Z. (2019) Functional analyses of an axonemal inner-arm dynein complex in the bloodstream form of
Trypanosoma brucei uncover its essential role in cytokinesis initiation. Molecular Microbiology, 112: 1718-1730
62. Hu H., An T., Kurasawa Y., Zhou Q., and Li Z. (2019) The trypanosome-specific proteins FPRC and CIF4 regulate cytokinesis initiation by
recruiting CIF1 to the cytokinesis initiation site. Journal of Biological Chemistry, 294: 16672-16683
cytokinesis initiation in Trypanosoma brucei. Journal of Cell Science, 132: jcs230581
60. Zhou Q., Pham K.T.M., Hu H., Kurasawa Y., and Li Z. (2019) A kinetochore-based ATM/ATR-independent DNA damage checkpoint
maintains genomic integrity in trypanosomes. Nucleic Acids Research, 47: 7973-7988
59. Zhang X., An T., Pham K.T.M., Lun Z.-R., and Li Z. (2019) Functional analyses of cytokinesis regulators in bloodstream stage Trypanosoma
brucei parasites identify functions and regulations specific to the life cycle stage. mSphere, 4: e00199-19 (Featured article)
58. Zhang X., Li, S.J., Li Z., He C.Y., Hide G., Lai D.H., and Lun Z.-R. (2019) Cell cycle and cleavage events during in vitro cultivation of
bloodstream forms of Trypanosoma lewisi, a zoonotic pathogen. Cell Cycle, 18: 552-567
2018
57. An T., Liu Y., Gourguechon S., Wang C.C., and Li Z. (2018) CDK phosphorylation of translation initiation factors couples protein translation
with cell-cycle transition. Cell Reports, 25: 3204-3214
56. Zhou Q.*, An T.*, Pham K.T.M., Hu H., and Li Z. (2018) The CIF1 protein is a master orchestrator of trypanosome cytokinesis that recruits
several cytokinesis regulators to the cytokinesis initiation site. Journal of Biological Chemistry, 293: 16177-16192 (*co-first authors)
55. Zhou Q.*, Lee K.J.*, Kurasawa Y.*, Hu H.*, An T., and Li Z. (2018) Faithful chromosome segregation in Trypanosoma brucei requires a
cohort of divergent spindle-associated proteins with distinct functions. Nucleic Acids Research, 46: 8216-8231 (*co-first authors)
54. An T. and Li Z. (2018) An orphan kinesin controls trypanosome morphology transitions by targeting FLAM3 to the flagellum. PLoS
Pathogens, 14(5): e1007101
53. Kurasawa Y., Hu H., Zhou Q., and Li Z. (2018) The trypanosome-specific protein CIF3 cooperates with the CIF1 protein to promote
cytokinesis in Trypanosoma brucei. Journal of Biological Chemistry, 293: 10275-10286
52. Zhou Q., Dong G., and Li Z. (2018) Flagellum inheritance in Trypanosoma brucei requires a kinetoplastid-specific protein phosphatase.
Journal of Biological Chemistry, 293: 8508-8520
2017
51. Hu H., Majneri P., Li D., Kurasawa Y., An T., Dong G., and Li Z. (2017) Functional analyses of the CIF1-CIF2 complex in Trypanosoma
brucei identify the structural motifs required for cytokinesis. Journal of Cell Science, 130: 4108-4119
50. Liu Z. Han X., Zhou Q., Chen R., Fruge S., Chan Jo, M., Ma Y., Li Z., Yokoi K., and Qin L. (2017) Integrated microfluidic system for gene
silencing and cell migration. Advanced Biosystems, 1(6): 1700054
49. Hu H., Zhou Q., Han X., and Li Z. (2017) CRL4-WDR1 controls Polo-like kinase abundance to promote bilobe duplication, basal body
segregation and flagellum attachment in Trypanosoma brucei. PLoS Pathogens, 13: e1006146
substrate identification. Journal of Biological Chemistry, 292: 1081-1091
47. Dang H.Q., Zhou Q., Rowlett V.W., Hu H., Lee K.J., Margolin W., and Li Z. (2017) Proximity interactions among basal body components in
Trypanosoma brucei identify novel regulators of basal body biogenesis and inheritance. mBio, 8: e02120-16
2016
46. Hu H.*, Gourguechon S.*, Wang C.C., and Li Z. (2016) The G1 cyclin-dependent kinase CRK1 in Trypanosoma brucei regulates
anterograde protein transport by phosphorylating the COPII subunit Sec31. Journal of Biological Chemistry, 291: 15527-15539 (*co-first
authors)
45. Zhou Q., Hu H., and Li Z. (2016) An EF-hand-containing protein in Trypanosoma brucei regulates cytokinesis initiation by maintaining the
stability of the cytokinesis initiation factor CIF1. Journal of Biological Chemistry, 291: 14395-14409
44. Zhou Q. and Li Z. (2016) A backup cytokinesis pathway in Trypanosoma brucei. Cell Cycle, 15: 2379-2380
43. Zhou Q., Gu J., Lun Z.-R., Ayala F.J., and Li Z. (2016) Two distinct cytokinesis pathways drive trypanosome cell division initiation from
opposite cell ends. Proc. Natl. Acad. Sci. U.S.A., 113: 3287-3292
2015
42. Hu H., Zhou Q., and Li Z. (2015) SAS-4 protein in Trypanosoma brucei controls life cycle transitions by modulating the length of the
flagellum attachment zone filament. Journal of Biological Chemistry, 290: 30453-30463
41. Hu H., Zhou Q., and Li Z. (2015) A novel basal body protein that is a Polo-like kinase substrate is required for basal body segregation and
flagellum adhesion in Trypanosoma brucei. Journal of Biological Chemistry, 290: 25012-25022
40. Zhou Q. and Li Z. (2015) γ-tubulin complex in Trypanosome brucei: molecular composition, subunit interdependence and requirement for
axonemal central pair protein assembly. Molecular Microbiology, 98: 667-680
39. Hu H., Liu Y., Zhou Q., Siegel S. and Li Z. (2015) The centriole cartwheel protein SAS-6 in Trypanosoma brucei is required for probasal
body biogenesis and flagellum assembly. Eukaryotic Cell, 14: 898-907
Journal of Cell Science, 128: 2361-2372
2014
37. Wei Y., Hu H., Lun Z.-R., and Li Z. (2014) Centrin3 in trypanosomes maintains the stability of a flagellar inner-arm dynein for cell motility.
Nature Communications, 5: 4060
36. Han X. and Li Z. (2014) Comparative analysis of chromosome segregation in human, yeasts and trypanosome. Frontiers in Biology, 9:
472-480
35. Li Z. (2014) A novel role of centrin in flagellar motility: stabilizing an inner-arm dynein motor in the flagellar axoneme. Microbial Cell, 1(8):
267-269
Review of Cell and Molecular Biology, 308: 127-166
33. Hu H., Yu Z., Liu Y., Wang T., Wei Y., and Li Z. (2014) The Aurora B kinase in Trypanosoma brucei undergoes post-translational
modifications and is targeted to various subcellular locations through binding to TbCPC1. Molecular Microbiology, 91: 256-274
32. Wei Y. and Li Z. (2014) Distinct roles of a mitogen-activated protein kinase in cytokinesis between different life cycle forms of
Trypanosoma brucei. Eukaryotic Cell, 13: 110-118
2013
31. Liu Y., Hu H., and Li Z. (2013) The cooperative roles of PHO80-like cyclins in regulating the G1/S transition and posterior cytoskeletal
morphogenesis in Trypanosoma brucei. Molecular Microbiology, 90: 130-146
30. Wei Y., Hu H., Lun Z.-R., and Li Z. (2013) The cooperative roles of two kinetoplastid-specific kinesins in cytokinesis and in maintaining cell
morphology in bloodstream trypanosomes. PLoS ONE, 8: e73869
2012
29. Li Z. (2012) Regulation of the cell division cycle in Trypanosoma brucei. Eukaryotic Cell, 11: 1180-1190
28. Hu H., Hu L., Yu Z., Chasse A.E., Chu F., and Li Z. (2012) An orphan kinesin in trypanosomes cooperates with a kinetoplastid-specific
kinesin to maintain cell morphology by regulating subpellicular microtubules. Journal of Cell Science, 125: 4126-4136
27. Yu Z., Liu Y., and Li Z. (2012) Structure-function relationship of the Polo-like kinase in Trypanosoma brucei. Journal of Cell Science, 125:
1519-1530
26. Hu L., Hu H., and Li Z. (2012) A kinetoplastid-specific kinesin is required for cytokinesis and for maintenance of cell morphology in
Trypanosoma brucei. Molecular Microbiology, 83: 565-578
2011
25. Dang H.Q., and Li Z. (2011) The Cdc45.Mcm2-7.GINS protein complex in trypanosomes regulates DNA replication and interacts with two
Orc1-like proteins in the origin recognition complex. Journal of Biological Chemistry, 286: 32424-32435
Prior to UTHealth
24. Li Z., Umeyama T., Li Z., and Wang C.C. (2010) Polo-like kinase guides cytokinesis in Trypanosoma brucei through an indirect means.
Eukaryotic Cell, 9: 705-716
23. Li Z., Umeyama T., and Wang C.C. (2009) The Aurora kinase in Trypanosoma brucei plays distinctive roles in metaphase-anaphase
transition and cytokinetic initiation. PLoS Pathogens, 5: e1000575
22. Li Z., Umeyama T., and Wang C.C. (2008) The chromosomal passenger complex and a mitotic kinesin interact with the Tousled-like
kinase in trypanosomes to regulate mitosis and cytokinesis. PLoS ONE, 3: e3814
21. Li Z., and Wang C.C. (2008) KMP-11, a basal body and flagellar protein, is required for cell division in Trypanosoma brucei. Eukaryotic Cell,
7: 1941-1950
20. Li Z., Lee J.H., Chu F., Burlingame A.L., Günzl A., and Wang C.C. (2008) Identification of a novel chromosomal passenger complex and its
unique localization during cytokinesis in Trypanosoma brucei. PLoS ONE, 3: e2354
19. Li Z., Lindsay M.E., Motyka S.A., Englund P.T., and Wang C.C. (2008) Identification of a bacterial-like HslVU protease in the mitochondria
of Trypanosoma brucei and its role in mitochondrial DNA replication. PLoS Pathogens, 4: e1000048 18. Li Z., Gourguechon S., and Wang C.C. (2007) Tousled-like kinase in a microbial eukaryote regulates spindle assembly and S-phase
progression by interacting with Aurora kinase and chromatin assembly factors. Journal of Cell Science, 120: 3883-3894
17. Li Z.*, Tu X.*, and Wang C.C. (2006) Okadaic acid overcomes the blocked cell cycle caused by depleting cdc2-related kinases in
Trypanosoma brucei. Experimental Cell Research, 312: 3504-3516 (*co-first authors)
16. Li Z., and Wang C.C. (2006) Changing roles of Aurora-B kinase in two life cycle stages of Trypanosoma brucei. Eukaryotic Cell, 5: 1026-1
1035
15. Tu X., Kumar P., Li Z., and Wang C.C. (2006) An Aurora kinase homologue is involved in regulating both mitosis and cytokinesis in
Trypanosoma brucei. Journal of Biological Chemistry, 281: 9677-9687
14. Li Y., Li Z., and Wang C.C. (2003) Differentiation of Trypanosoma brucei may be stage non-specific and does not require progression of
cell cycle. Molecular Microbiology, 49: 251-265
13. Li Z., and Wang C.C. (2003) A PHO80-like cyclin and a B-type cyclin control the cell cycle of the procyclic form of Trypanosoma brucei.
Journal of Biological Chemistry, 278: 20652-20658
12. Li Z., and Wang C.C. (2002) Functional characterization of the 11 non-ATPase subunit proteins in the trypanosome 19S proteasomal
regulatory complex. Journal of Biological Chemistry, 277: 42686-42693
11. Li Z., Zou C.B., Yao Y., Hoyt M.A., McDonough S., Mackey Z.B., Coffino P., and Wang C.C. (2002) An easily dissociated 26S proteasome
catalyzes an essential ubiquitin-mediated protein degradation pathway in Trypanosoma brucei. Journal of Biological Chemistry, 277:
15486-15498
10. Li Z.Y., and Chen S.Y. (2001) Isolation, characterization and chromosomal location of a novel zinc-finger protein gene that is down-
regulated by salt stress. Theoretical and Applied Genetics, 102: 363-368
9. Li Z.Y., Chen S.Y., Zheng X.W., and Zhu L.H. (2000) Identification and chromosomal localization of a transcriptionally active
retrotransposon of Ty3-gypsy type in rice. Genome, 43: 404-408
8. Li Z.Y., and Chen S.Y. (2000) Isolation and characterization of a salt- and drought-inducible gene for S-adenosylmethionine decarboxylase
from wheat. Journal of Plant Physiology, 156: 386-393
7. Li Z.Y., and Chen S.Y. (2000) Differential accumulation of the S-adenosylmethionine decarboxylase transcript in rice seedlings in response
to salt and drought stresses. Theoretical and Applied Genetics, 100: 782-788
6. Zhang J.S., Xie C., Li Z.Y., and Chen S.Y. (1999) Expression of the plasma membrane H+-ATPase gene in response to salt stress in a rice
salt-tolerant mutant and its original variety. Theoretical and Applied Genetics, 99: 1006-1011
5. Li Z.Y., Zhang J.S., and Chen S.Y. (1999) Molecular cloning, expression analysis and chromosomal mapping of salt-responsive genes in
rice. Science in China (Series C, Life Sciences), 42: 506-516
4. Li Z.Y., and Chen S.Y. (1999) Inducible expression of the translation elongation factor 1A gene in rice seedlings in response to
environmental stresses. Journal of Integrative Plant Biology, 41: 800-806
3. Li Z.Y., and Chen S. (1999) Molecular cloning, chromosomal mapping and expression analysis of disease resistance gene homologues in
rice. Chinese Science Bulletin, 44: 1202-1207
2. Mei M., Chen L., Zhang Z.H., Li Z., Xu C.G., and Zhang Q. (1999) pms3 is the locus causing the original photoperiod-sensitive male sterility
mutation of ‘Nongken 58S’. Science in China (Series C, Life Sciences), 42:316-322
1. Li Z.Y., Lin X.H., Xie Y.F., and Zhang D.P. (1999) Tagging of a photoperiod-sensitive genic male sterile gene in Nongken 58S via molecular
markers. Journal of Integrative Plant Biology, 41: 731-735
78. Hu H.*, Kurasawa Y.*, Zhou Q., and Li Z. (2024) A kinesin-13 family kinesin in Trypanosoma brucei regulates cytokinesis and cytoskeleton
morphogenesis by promoting microtubule bundling. PLoS Pathogens, 20: e1012000 (*: co-first authors)
2023
77. Souza Onofre T.*, Pham K.T.M.*, Zhou Q., and Li Z. (2023) The microtubule quartet protein SNAP1 in Trypanosoma brucei facilitates
flagellum and cell division plane positioning by promoting basal body segregation. Journal of Biological Chemistry, 299: 105340
(*: co-first authors)
76. Lee K.J., Zhou Q., and Li Z. (2023) CRK2 controls cytoskeleton morphogenesis in Trypanosoma brucei by phosphorylating β-tubulin to
regulate microtubule dynamics. PLoS Pathogens, 19: e1011270
2022
75. Kurasawa Y.*, Lee K.J.*, Hu H., Pham K.T.M., and Li Z. (2022) Polo-like kinase and Aurora B kinase phosphorylate and cooperate
with the CIF1-CIF2 complex to promote cytokinesis initiation in Trypanosoma brucei. Open Biology, 12: 220197 (*: co-first authors)
74. Pham K.T.M., Zhou Q., Lee K.J., and Li Z. (2022) A Spef1-interacting microtubule quartet protein in Trypanosoma brucei promotes
flagellar inheritance by regulating basal body segregation. Journal of Biological Chemistry, 298: 102125
73. Zhou Q.*, Hu H.*, and Li Z. (2022) KLIF-associated cytoskeletal proteins in Trypanosoma brucei regulate cytokinesis by promoting
cleavage furrow positioning and ingression. Journal of Biological Chemistry, 298: 101943 (*: co-first authors)
72. Kurasawa Y., Lee, K.J., and Li Z. (2022) Structural domains of CIF3 required for interaction with cytokinesis regulatory proteins and
for cytokinesis initiation in Trypanosoma brucei. mSphere, 7: 00047-22
- Featured as Cover article.
rapid passage in mice. Frontiers in Microbiology, 12: 806626
2021
70. Merrick C.J., Absalon S., Brochet M. Li Z., and Suvorova E.S. (2021) Celebrating microbial diversity: the many cell cycles of the eukaryotic
microbes. Frontiers in Cellular and Infection Microbiology, 11: 738994
69. Lee K.J., and Li Z. (2021) The CRK2-CYC13 complex functions as an S-phase cyclin-dependent kinase to promote DNA replication in
Trypanosoma brucei. BMC Biology, 19: 29
68. An T., Hu H., and Li Z. (2021) The kinetoplastid-specific phosphatase KPP1 attenuates PLK activity to facilitate flagellum inheritance
in Trypanosoma brucei. Science Signaling, 14: eabc6435
- Featured as Cover article.
2020
67. Kurasawa Y., An T., and Li Z. (2020) Polo-like kinase in trypanosomes: an odd member out of the Polo family. Open Biology,
10: 200189
66. Pham K.T.M., Hu H., and Li Z. (2020) Maintenance of hook complex integrity and centrin arm assembly facilitates flagellum
inheritance in Trypanosoma brucei. Journal of Biological Chemistry, 295: 12962-12974
65. An T.*, Zhou Q.*, Hu H., Cormaty H., and Li Z. (2020) FAZ27 cooperates with FLAM3 and ClpGM6 to maintain cell morphology in
Trypanosoma brucei. Journal of Cell Science, 133: jcs245258 (* co-first authors)
64. Pham K.T.M. and Li Z. (2020) Regulated protein stabilization underpins the functional interplay among basal body components in
Trypanosoma brucei. Journal of Biological Chemistry, 295: 729-742
2019
63. Zhang X., Hu H., Lun Z.-R., and Li Z. (2019) Functional analyses of an axonemal inner-arm dynein complex in the bloodstream form of
Trypanosoma brucei uncover its essential role in cytokinesis initiation. Molecular Microbiology, 112: 1718-1730
62. Hu H., An T., Kurasawa Y., Zhou Q., and Li Z. (2019) The trypanosome-specific proteins FPRC and CIF4 regulate cytokinesis initiation by
recruiting CIF1 to the cytokinesis initiation site. Journal of Biological Chemistry, 294: 16672-16683
- Featured as Cover article.
cytokinesis initiation in Trypanosoma brucei. Journal of Cell Science, 132: jcs230581
60. Zhou Q., Pham K.T.M., Hu H., Kurasawa Y., and Li Z. (2019) A kinetochore-based ATM/ATR-independent DNA damage checkpoint
maintains genomic integrity in trypanosomes. Nucleic Acids Research, 47: 7973-7988
59. Zhang X., An T., Pham K.T.M., Lun Z.-R., and Li Z. (2019) Functional analyses of cytokinesis regulators in bloodstream stage Trypanosoma
brucei parasites identify functions and regulations specific to the life cycle stage. mSphere, 4: e00199-19 (Featured article)
58. Zhang X., Li, S.J., Li Z., He C.Y., Hide G., Lai D.H., and Lun Z.-R. (2019) Cell cycle and cleavage events during in vitro cultivation of
bloodstream forms of Trypanosoma lewisi, a zoonotic pathogen. Cell Cycle, 18: 552-567
2018
57. An T., Liu Y., Gourguechon S., Wang C.C., and Li Z. (2018) CDK phosphorylation of translation initiation factors couples protein translation
with cell-cycle transition. Cell Reports, 25: 3204-3214
56. Zhou Q.*, An T.*, Pham K.T.M., Hu H., and Li Z. (2018) The CIF1 protein is a master orchestrator of trypanosome cytokinesis that recruits
several cytokinesis regulators to the cytokinesis initiation site. Journal of Biological Chemistry, 293: 16177-16192 (*co-first authors)
55. Zhou Q.*, Lee K.J.*, Kurasawa Y.*, Hu H.*, An T., and Li Z. (2018) Faithful chromosome segregation in Trypanosoma brucei requires a
cohort of divergent spindle-associated proteins with distinct functions. Nucleic Acids Research, 46: 8216-8231 (*co-first authors)
54. An T. and Li Z. (2018) An orphan kinesin controls trypanosome morphology transitions by targeting FLAM3 to the flagellum. PLoS
Pathogens, 14(5): e1007101
53. Kurasawa Y., Hu H., Zhou Q., and Li Z. (2018) The trypanosome-specific protein CIF3 cooperates with the CIF1 protein to promote
cytokinesis in Trypanosoma brucei. Journal of Biological Chemistry, 293: 10275-10286
52. Zhou Q., Dong G., and Li Z. (2018) Flagellum inheritance in Trypanosoma brucei requires a kinetoplastid-specific protein phosphatase.
Journal of Biological Chemistry, 293: 8508-8520
2017
51. Hu H., Majneri P., Li D., Kurasawa Y., An T., Dong G., and Li Z. (2017) Functional analyses of the CIF1-CIF2 complex in Trypanosoma
brucei identify the structural motifs required for cytokinesis. Journal of Cell Science, 130: 4108-4119
50. Liu Z. Han X., Zhou Q., Chen R., Fruge S., Chan Jo, M., Ma Y., Li Z., Yokoi K., and Qin L. (2017) Integrated microfluidic system for gene
silencing and cell migration. Advanced Biosystems, 1(6): 1700054
49. Hu H., Zhou Q., Han X., and Li Z. (2017) CRL4-WDR1 controls Polo-like kinase abundance to promote bilobe duplication, basal body
segregation and flagellum attachment in Trypanosoma brucei. PLoS Pathogens, 13: e1006146
- Featured as Cover article.
substrate identification. Journal of Biological Chemistry, 292: 1081-1091
47. Dang H.Q., Zhou Q., Rowlett V.W., Hu H., Lee K.J., Margolin W., and Li Z. (2017) Proximity interactions among basal body components in
Trypanosoma brucei identify novel regulators of basal body biogenesis and inheritance. mBio, 8: e02120-16
2016
46. Hu H.*, Gourguechon S.*, Wang C.C., and Li Z. (2016) The G1 cyclin-dependent kinase CRK1 in Trypanosoma brucei regulates
anterograde protein transport by phosphorylating the COPII subunit Sec31. Journal of Biological Chemistry, 291: 15527-15539 (*co-first
authors)
45. Zhou Q., Hu H., and Li Z. (2016) An EF-hand-containing protein in Trypanosoma brucei regulates cytokinesis initiation by maintaining the
stability of the cytokinesis initiation factor CIF1. Journal of Biological Chemistry, 291: 14395-14409
44. Zhou Q. and Li Z. (2016) A backup cytokinesis pathway in Trypanosoma brucei. Cell Cycle, 15: 2379-2380
43. Zhou Q., Gu J., Lun Z.-R., Ayala F.J., and Li Z. (2016) Two distinct cytokinesis pathways drive trypanosome cell division initiation from
opposite cell ends. Proc. Natl. Acad. Sci. U.S.A., 113: 3287-3292
- Featured as Cover article.
- Recommended by Faculty of 1000.
2015
42. Hu H., Zhou Q., and Li Z. (2015) SAS-4 protein in Trypanosoma brucei controls life cycle transitions by modulating the length of the
flagellum attachment zone filament. Journal of Biological Chemistry, 290: 30453-30463
41. Hu H., Zhou Q., and Li Z. (2015) A novel basal body protein that is a Polo-like kinase substrate is required for basal body segregation and
flagellum adhesion in Trypanosoma brucei. Journal of Biological Chemistry, 290: 25012-25022
40. Zhou Q. and Li Z. (2015) γ-tubulin complex in Trypanosome brucei: molecular composition, subunit interdependence and requirement for
axonemal central pair protein assembly. Molecular Microbiology, 98: 667-680
39. Hu H., Liu Y., Zhou Q., Siegel S. and Li Z. (2015) The centriole cartwheel protein SAS-6 in Trypanosoma brucei is required for probasal
body biogenesis and flagellum assembly. Eukaryotic Cell, 14: 898-907
- Spotlight article: Conserved functions but distinct regulations of SAS-6 in trypanosomes
Journal of Cell Science, 128: 2361-2372
- Highlighted article: Trypanosomes: what's all that FAZ about?
2014
37. Wei Y., Hu H., Lun Z.-R., and Li Z. (2014) Centrin3 in trypanosomes maintains the stability of a flagellar inner-arm dynein for cell motility.
Nature Communications, 5: 4060
36. Han X. and Li Z. (2014) Comparative analysis of chromosome segregation in human, yeasts and trypanosome. Frontiers in Biology, 9:
472-480
35. Li Z. (2014) A novel role of centrin in flagellar motility: stabilizing an inner-arm dynein motor in the flagellar axoneme. Microbial Cell, 1(8):
267-269
- Featured as Cover article.
Review of Cell and Molecular Biology, 308: 127-166
33. Hu H., Yu Z., Liu Y., Wang T., Wei Y., and Li Z. (2014) The Aurora B kinase in Trypanosoma brucei undergoes post-translational
modifications and is targeted to various subcellular locations through binding to TbCPC1. Molecular Microbiology, 91: 256-274
32. Wei Y. and Li Z. (2014) Distinct roles of a mitogen-activated protein kinase in cytokinesis between different life cycle forms of
Trypanosoma brucei. Eukaryotic Cell, 13: 110-118
2013
31. Liu Y., Hu H., and Li Z. (2013) The cooperative roles of PHO80-like cyclins in regulating the G1/S transition and posterior cytoskeletal
morphogenesis in Trypanosoma brucei. Molecular Microbiology, 90: 130-146
30. Wei Y., Hu H., Lun Z.-R., and Li Z. (2013) The cooperative roles of two kinetoplastid-specific kinesins in cytokinesis and in maintaining cell
morphology in bloodstream trypanosomes. PLoS ONE, 8: e73869
2012
29. Li Z. (2012) Regulation of the cell division cycle in Trypanosoma brucei. Eukaryotic Cell, 11: 1180-1190
28. Hu H., Hu L., Yu Z., Chasse A.E., Chu F., and Li Z. (2012) An orphan kinesin in trypanosomes cooperates with a kinetoplastid-specific
kinesin to maintain cell morphology by regulating subpellicular microtubules. Journal of Cell Science, 125: 4126-4136
27. Yu Z., Liu Y., and Li Z. (2012) Structure-function relationship of the Polo-like kinase in Trypanosoma brucei. Journal of Cell Science, 125:
1519-1530
26. Hu L., Hu H., and Li Z. (2012) A kinetoplastid-specific kinesin is required for cytokinesis and for maintenance of cell morphology in
Trypanosoma brucei. Molecular Microbiology, 83: 565-578
2011
25. Dang H.Q., and Li Z. (2011) The Cdc45.Mcm2-7.GINS protein complex in trypanosomes regulates DNA replication and interacts with two
Orc1-like proteins in the origin recognition complex. Journal of Biological Chemistry, 286: 32424-32435
Prior to UTHealth
24. Li Z., Umeyama T., Li Z., and Wang C.C. (2010) Polo-like kinase guides cytokinesis in Trypanosoma brucei through an indirect means.
Eukaryotic Cell, 9: 705-716
23. Li Z., Umeyama T., and Wang C.C. (2009) The Aurora kinase in Trypanosoma brucei plays distinctive roles in metaphase-anaphase
transition and cytokinetic initiation. PLoS Pathogens, 5: e1000575
22. Li Z., Umeyama T., and Wang C.C. (2008) The chromosomal passenger complex and a mitotic kinesin interact with the Tousled-like
kinase in trypanosomes to regulate mitosis and cytokinesis. PLoS ONE, 3: e3814
21. Li Z., and Wang C.C. (2008) KMP-11, a basal body and flagellar protein, is required for cell division in Trypanosoma brucei. Eukaryotic Cell,
7: 1941-1950
20. Li Z., Lee J.H., Chu F., Burlingame A.L., Günzl A., and Wang C.C. (2008) Identification of a novel chromosomal passenger complex and its
unique localization during cytokinesis in Trypanosoma brucei. PLoS ONE, 3: e2354
19. Li Z., Lindsay M.E., Motyka S.A., Englund P.T., and Wang C.C. (2008) Identification of a bacterial-like HslVU protease in the mitochondria
of Trypanosoma brucei and its role in mitochondrial DNA replication. PLoS Pathogens, 4: e1000048 18. Li Z., Gourguechon S., and Wang C.C. (2007) Tousled-like kinase in a microbial eukaryote regulates spindle assembly and S-phase
progression by interacting with Aurora kinase and chromatin assembly factors. Journal of Cell Science, 120: 3883-3894
17. Li Z.*, Tu X.*, and Wang C.C. (2006) Okadaic acid overcomes the blocked cell cycle caused by depleting cdc2-related kinases in
Trypanosoma brucei. Experimental Cell Research, 312: 3504-3516 (*co-first authors)
16. Li Z., and Wang C.C. (2006) Changing roles of Aurora-B kinase in two life cycle stages of Trypanosoma brucei. Eukaryotic Cell, 5: 1026-1
1035
15. Tu X., Kumar P., Li Z., and Wang C.C. (2006) An Aurora kinase homologue is involved in regulating both mitosis and cytokinesis in
Trypanosoma brucei. Journal of Biological Chemistry, 281: 9677-9687
14. Li Y., Li Z., and Wang C.C. (2003) Differentiation of Trypanosoma brucei may be stage non-specific and does not require progression of
cell cycle. Molecular Microbiology, 49: 251-265
13. Li Z., and Wang C.C. (2003) A PHO80-like cyclin and a B-type cyclin control the cell cycle of the procyclic form of Trypanosoma brucei.
Journal of Biological Chemistry, 278: 20652-20658
12. Li Z., and Wang C.C. (2002) Functional characterization of the 11 non-ATPase subunit proteins in the trypanosome 19S proteasomal
regulatory complex. Journal of Biological Chemistry, 277: 42686-42693
11. Li Z., Zou C.B., Yao Y., Hoyt M.A., McDonough S., Mackey Z.B., Coffino P., and Wang C.C. (2002) An easily dissociated 26S proteasome
catalyzes an essential ubiquitin-mediated protein degradation pathway in Trypanosoma brucei. Journal of Biological Chemistry, 277:
15486-15498
10. Li Z.Y., and Chen S.Y. (2001) Isolation, characterization and chromosomal location of a novel zinc-finger protein gene that is down-
regulated by salt stress. Theoretical and Applied Genetics, 102: 363-368
9. Li Z.Y., Chen S.Y., Zheng X.W., and Zhu L.H. (2000) Identification and chromosomal localization of a transcriptionally active
retrotransposon of Ty3-gypsy type in rice. Genome, 43: 404-408
8. Li Z.Y., and Chen S.Y. (2000) Isolation and characterization of a salt- and drought-inducible gene for S-adenosylmethionine decarboxylase
from wheat. Journal of Plant Physiology, 156: 386-393
7. Li Z.Y., and Chen S.Y. (2000) Differential accumulation of the S-adenosylmethionine decarboxylase transcript in rice seedlings in response
to salt and drought stresses. Theoretical and Applied Genetics, 100: 782-788
6. Zhang J.S., Xie C., Li Z.Y., and Chen S.Y. (1999) Expression of the plasma membrane H+-ATPase gene in response to salt stress in a rice
salt-tolerant mutant and its original variety. Theoretical and Applied Genetics, 99: 1006-1011
5. Li Z.Y., Zhang J.S., and Chen S.Y. (1999) Molecular cloning, expression analysis and chromosomal mapping of salt-responsive genes in
rice. Science in China (Series C, Life Sciences), 42: 506-516
4. Li Z.Y., and Chen S.Y. (1999) Inducible expression of the translation elongation factor 1A gene in rice seedlings in response to
environmental stresses. Journal of Integrative Plant Biology, 41: 800-806
3. Li Z.Y., and Chen S. (1999) Molecular cloning, chromosomal mapping and expression analysis of disease resistance gene homologues in
rice. Chinese Science Bulletin, 44: 1202-1207
2. Mei M., Chen L., Zhang Z.H., Li Z., Xu C.G., and Zhang Q. (1999) pms3 is the locus causing the original photoperiod-sensitive male sterility
mutation of ‘Nongken 58S’. Science in China (Series C, Life Sciences), 42:316-322
1. Li Z.Y., Lin X.H., Xie Y.F., and Zhang D.P. (1999) Tagging of a photoperiod-sensitive genic male sterile gene in Nongken 58S via molecular
markers. Journal of Integrative Plant Biology, 41: 731-735